The IP3 Receptor Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to ITPR1. This antibody recognizes Human, Mouse, and Rat antigen. The IP3 Receptor Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated has been validated for the following applications: Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity)